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Spatial transcriptome profiling by MERFISH reveals fetal liver hematopoietic stem cell niche architecture

The hematopoietic stem cell (HSC) niche has been extensively studied in bone marrow, yet a more systematic investigation into the microenvironment regulation of hematopoiesis in fetal liver is necessary. Here we investigate the spatial organization and transcriptional profile of individual cells in...

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Detalles Bibliográficos
Autores principales: Lu, Yanfang, Liu, Miao, Yang, Jennifer, Weissman, Sherman M., Pan, Xinghua, Katz, Samuel G., Wang, Siyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238952/
https://www.ncbi.nlm.nih.gov/pubmed/34183665
http://dx.doi.org/10.1038/s41421-021-00266-1