Restoration of the molecular clock is tumor suppressive in neuroblastoma

MYCN activation is a hallmark of advanced neuroblastoma (NB) and a known master regulator of metabolic reprogramming, favoring NB adaptation to its microenvironment. We found that the expression of the main regulators of the molecular clock loops is profoundly disrupted in MYCN-amplified NB patients...

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Detalles Bibliográficos
Autores principales: Moreno-Smith, Myrthala, Milazzo, Giorgio, Tao, Ling, Fekry, Baharan, Zhu, Bokai, Mohammad, Mahmoud A., Di Giacomo, Simone, Borkar, Roshan, Reddy, Karthik Reddy Kami, Capasso, Mario, Vasudevan, Sanjeev A., Sumazin, Pavel, Hicks, John, Putluri, Nagireddy, Perini, Giovanni, Eckel-Mahan, Kristin, Burris, Thomas P., Barbieri, Eveline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238982/
https://www.ncbi.nlm.nih.gov/pubmed/34183658
http://dx.doi.org/10.1038/s41467-021-24196-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238982/
https://www.ncbi.nlm.nih.gov/pubmed/34183658
http://dx.doi.org/10.1038/s41467-021-24196-4

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