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The long non-coding RNA βFaar regulates islet β-cell function and survival during obesity in mice

Despite obesity being a predisposing factor for pancreatic β-cell dysfunction and loss, the mechanisms underlying its negative effect on insulin-secreting cells remain poorly understood. In this study, we identify an islet-enriched long non-coding RNA (lncRNA), which we name β-cell function and apop...

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Detalles Bibliográficos
Autores principales: Zhang, Fangfang, Yang, Yue, Chen, Xi, Liu, Yue, Hu, Qianxing, Huang, Bin, Liu, Yuhong, Pan, Yi, Zhang, Yanfeng, Liu, Dechen, Liang, Rui, Li, Guoqing, Wei, Qiong, Li, Ling, Jin, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238983/
https://www.ncbi.nlm.nih.gov/pubmed/34183666
http://dx.doi.org/10.1038/s41467-021-24302-6