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Exploring the chemical space of protein–protein interaction inhibitors through machine learning
Although protein–protein interactions (PPIs) have emerged as the basis of potential new therapeutic approaches, targeting intracellular PPIs with small molecule inhibitors is conventionally considered highly challenging. Driven by increasing research efforts, success rates have increased significant...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238997/ https://www.ncbi.nlm.nih.gov/pubmed/34183730 http://dx.doi.org/10.1038/s41598-021-92825-5 |