Decreased ferroportin in hepatocytes promotes macrophages polarize towards an M2-like phenotype and liver fibrosis

Iron release from macrophages is closely regulated by the interaction of hepcidin, a peptide hormone produced by hepatocytes, with the macrophage iron exporter ferroportin (FPN1). However, the functions of FPN1 in hepatocyte secretion and macrophage polarization remain unknown. CD68 immunohistochemi...

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Detalles Bibliográficos
Autores principales: Cai, Chengyuan, Zeng, Danning, Gao, Qing, Ma, Lei, Zeng, Bohang, Zhou, Yi, Wang, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239022/
https://www.ncbi.nlm.nih.gov/pubmed/34183746
http://dx.doi.org/10.1038/s41598-021-92839-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239022/
https://www.ncbi.nlm.nih.gov/pubmed/34183746
http://dx.doi.org/10.1038/s41598-021-92839-z

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