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Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation

Type II alveolar cells (AT2s) are critical for basic respiratory homeostasis and tissue repair after lung injury. Prior studies indicate that AT2s also express major histocompatibility complex class II (MHCII) molecules, but how MHCII expression by AT2s is regulated and how it contributes to host de...

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Detalles Bibliográficos
Autores principales: Toulmin, Sushila A., Bhadiadra, Chaitali, Paris, Andrew J., Lin, Jeffrey H., Katzen, Jeremy, Basil, Maria C., Morrisey, Edward E., Worthen, G. Scott, Eisenlohr, Laurence C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239023/
https://www.ncbi.nlm.nih.gov/pubmed/34183650
http://dx.doi.org/10.1038/s41467-021-23619-6