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Testicular somatic cell-like cells derived from embryonic stem cells induce differentiation of epiblasts into germ cells

Regeneration of the testis from pluripotent stem cells is a real challenge, reflecting the complexity of the interaction of germ cells and somatic cells. Here we report the generation of testicular somatic cell-like cells (TesLCs) including Sertoli cell-like cells (SCLCs) from mouse embryonic stem c...

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Detalles Bibliográficos
Autores principales: Rore, Holly, Owen, Nicholas, Piña-Aguilar, Raul Eduardo, Docherty, Kevin, Sekido, Ryohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239049/
https://www.ncbi.nlm.nih.gov/pubmed/34183774
http://dx.doi.org/10.1038/s42003-021-02322-8