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The mechanism of increased intestinal palmitic acid absorption and its impact on hepatic stellate cell activation in nonalcoholic steatohepatitis

Dietary palmitic acid (PA) promotes liver fibrosis in patients with nonalcoholic steatohepatitis (NASH). Herein, we clarified the intestinal absorption kinetics of dietary PA and effect of trans-portal PA on the activation of hepatic stellate cells (HSCs) involved in liver fibrosis in NASH. Blood PA...

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Detalles Bibliográficos
Autores principales: Hanayama, Masakazu, Yamamoto, Yasunori, Utsunomiya, Hiroki, Yoshida, Osamu, Liu, Shuang, Mogi, Masaki, Matsuura, Bunzo, Takeshita, Eiji, Ikeda, Yoshiou, Hiasa, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239050/
https://www.ncbi.nlm.nih.gov/pubmed/34183709
http://dx.doi.org/10.1038/s41598-021-92790-z