Cargando…

Modeling Liver Organogenesis by Recreating Three-Dimensional Collective Cell Migration: A Role for TGFβ Pathway

Three-dimensional (3D) collective cell migration (CCM) is critical for improving liver cell therapies, eliciting mechanisms of liver disease, and modeling human liver development and organogenesis. Mechanisms of CCM differ in 2D vs. 3D systems, and existing models are limited to 2D or transwell-base...

Descripción completa

Detalles Bibliográficos
Autores principales: Ogoke, Ogechi, Yousef, Osama, Ott, Cortney, Kalinousky, Allison, Lin, Wayne, Shamul, Claire, Ross, Shatoni, Parashurama, Natesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239196/
https://www.ncbi.nlm.nih.gov/pubmed/34211963
http://dx.doi.org/10.3389/fbioe.2021.621286