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Molecular chaperone RAP interacts with LRP1 in a dynamic bivalent mode and enhances folding of ligand-binding regions of other LDLR family receptors

The low-density lipoprotein receptor (LDLR) family of receptors are cell-surface receptors that internalize numerous ligands and play crucial role in various processes, such as lipoprotein metabolism, hemostasis, fetal development, etc. Previously, receptor-associated protein (RAP) was described as...

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Detalles Bibliográficos
Autores principales: Marakasova, Ekaterina, Olivares, Philip, Karnaukhova, Elena, Chun, Haarin, Hernandez, Nancy E., Kurasawa, James H., Hassink, Gabriela U., Shestopal, Svetlana A., Strickland, Dudley K., Sarafanov, Andrey G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239462/
https://www.ncbi.nlm.nih.gov/pubmed/34058195
http://dx.doi.org/10.1016/j.jbc.2021.100842