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MAP4K1 functions as a tumor promotor and drug mediator for AML via modulation of DNA damage/repair system and MAPK pathway

Background: Acute myeloid leukemia (AML) is a group of heterogeneous hematologic malignancies correlates with poor prognosis. It is important to identify biomarkers for effective treatment of AML. Kinases participate in many regulatory pathways and biological activities in AML. Previous studies demo...

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Detalles Bibliográficos
Autores principales: Ling, Qing, Li, Fenglin, Zhang, Xiang, Mao, Shihui, Lin, Xiangjie, Pan, Jiajia, Ye, Wenle, Wei, Wenwen, Qian, Yu, Hu, Chao, Huang, Xin, Wang, Jinghan, Wang, Huafeng, Huang, Jiansong, Wang, Yungui, Jin, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239467/
https://www.ncbi.nlm.nih.gov/pubmed/34166980
http://dx.doi.org/10.1016/j.ebiom.2021.103441