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Gsα-dependent signaling is required for postnatal establishment of a functional β-cell mass

OBJECTIVE: Early postnatal life is a critical period for the establishment of the functional β-cell mass that will sustain whole-body glucose homeostasis during the lifetime. β cells are formed from progenitors during embryonic development but undergo significant expansion in quantity and attain fun...

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Detalles Bibliográficos
Autores principales: Serra-Navarro, Berta, Fernandez-Ruiz, Rebeca, García-Alamán, Ainhoa, Pradas-Juni, Marta, Fernandez-Rebollo, Eduardo, Esteban, Yaiza, Mir-Coll, Joan, Mathieu, Julia, Dalle, Stephane, Hahn, Max, Ahlgren, Ulf, Weinstein, Lee S., Vidal, Josep, Gomis, Ramon, Gasa, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239471/
https://www.ncbi.nlm.nih.gov/pubmed/34091063
http://dx.doi.org/10.1016/j.molmet.2021.101264