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Gsα-dependent signaling is required for postnatal establishment of a functional β-cell mass
OBJECTIVE: Early postnatal life is a critical period for the establishment of the functional β-cell mass that will sustain whole-body glucose homeostasis during the lifetime. β cells are formed from progenitors during embryonic development but undergo significant expansion in quantity and attain fun...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239471/ https://www.ncbi.nlm.nih.gov/pubmed/34091063 http://dx.doi.org/10.1016/j.molmet.2021.101264 |