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Fasudil prevents liver fibrosis via activating natural killer cells and suppressing hepatic stellate cells

BACKGROUND: Fasudil, as a Ras homology family member A (RhoA) kinase inhibitor, is used to improve brain microcirculation and promote nerve regeneration clinically. Increasing evidence shows that Rho-kinase inhibition could improve liver fibrosis. AIM: To evaluate the anti-fibrotic effects of Fasudi...

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Detalles Bibliográficos
Autores principales: Han, Qiu-Ju, Mu, Yong-Liang, Zhao, Hua-Jun, Zhao, Rong-Rong, Guo, Quan-Juan, Su, Yu-Hang, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240055/
https://www.ncbi.nlm.nih.gov/pubmed/34239271
http://dx.doi.org/10.3748/wjg.v27.i24.3581