Genetically Encoded, pH-Sensitive mTFP1 Biosensor for Probing Lysosomal pH

[Image: see text] Lysosomes are important sites for macromolecular degradation, defined by an acidic lumenal pH of ∼4.5. To better understand lysosomal pH, we designed a novel, genetically encoded, fluorescent protein (FP)-based pH biosensor called Fluorescence Indicator REporting pH in Lysosomes (F...

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Detalles Bibliográficos
Autores principales: Chin, Marcus Y., Patwardhan, Anand R., Ang, Kean-Hooi, Wang, Austin L., Alquezar, Carolina, Welch, Mackenzie, Nguyen, Phi T., Grabe, Michael, Molofsky, Anna V., Arkin, Michelle R., Kao, Aimee W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240087/
https://www.ncbi.nlm.nih.gov/pubmed/34102054
http://dx.doi.org/10.1021/acssensors.0c02318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240087/
https://www.ncbi.nlm.nih.gov/pubmed/34102054
http://dx.doi.org/10.1021/acssensors.0c02318

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