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Effects of sterol derivatives in cationic liposomes on biodistribution and gene-knockdown in the lungs of mice systemically injected with siRNA lipoplexes

Cationic liposomes can be intravenously injected to deliver short interfering (si)RNAs into the lungs. The present study investigated the effects of sterol derivatives in systemically injected siRNA/cationic liposome complexes (siRNA lipoplexes) on gene-knockdown in the lungs of mice. Cationic lipos...

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Detalles Bibliográficos
Autores principales: Hattori, Yoshiyuki, Saito, Hiromu, Oku, Teruaki, Ozaki, Kei-Ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240178/
https://www.ncbi.nlm.nih.gov/pubmed/34165169
http://dx.doi.org/10.3892/mmr.2021.12237