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Effects of sterol derivatives in cationic liposomes on biodistribution and gene-knockdown in the lungs of mice systemically injected with siRNA lipoplexes
Cationic liposomes can be intravenously injected to deliver short interfering (si)RNAs into the lungs. The present study investigated the effects of sterol derivatives in systemically injected siRNA/cationic liposome complexes (siRNA lipoplexes) on gene-knockdown in the lungs of mice. Cationic lipos...
Autores principales: | Hattori, Yoshiyuki, Saito, Hiromu, Oku, Teruaki, Ozaki, Kei-Ichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240178/ https://www.ncbi.nlm.nih.gov/pubmed/34165169 http://dx.doi.org/10.3892/mmr.2021.12237 |
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