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Autophagy activity contributes to the impairment of social recognition in Epac2(−/−) mice

Autophagy is a lysosomal degradation pathway that regulates cellular homeostasis. It is constitutively active in neurons and controls the essential steps of neuronal development, leading to its dysfunction in neurodevelopmental disorders. Although mTOR-associated impaired autophagy has previously be...

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Detalles Bibliográficos
Autores principales: Kwak, Ji-Hye, Lee, You-kyung, Jun, Mi-Hee, Roh, Mootaek, Seo, Hyunhyo, Lee, Juhyun, Lee, Kyungmin, Lee, Jin-A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240198/
https://www.ncbi.nlm.nih.gov/pubmed/34183057
http://dx.doi.org/10.1186/s13041-021-00814-6