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Autophagy activity contributes to the impairment of social recognition in Epac2(−/−) mice
Autophagy is a lysosomal degradation pathway that regulates cellular homeostasis. It is constitutively active in neurons and controls the essential steps of neuronal development, leading to its dysfunction in neurodevelopmental disorders. Although mTOR-associated impaired autophagy has previously be...
Autores principales: | Kwak, Ji-Hye, Lee, You-kyung, Jun, Mi-Hee, Roh, Mootaek, Seo, Hyunhyo, Lee, Juhyun, Lee, Kyungmin, Lee, Jin-A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240198/ https://www.ncbi.nlm.nih.gov/pubmed/34183057 http://dx.doi.org/10.1186/s13041-021-00814-6 |
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