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Tanshinone I exerts cardiovascular protective effects in vivo and in vitro through inhibiting necroptosis via Akt/Nrf2 signaling pathway

BACKGROUND: Tanshinone I (TI) is a primary component of Salvia miltiorrhiza Bunge (Danshen), which confers a favorable role in a variety of pharmacological activities including cardiovascular protection. However, the exact mechanism of the cardiovascular protection activity of TI remains to be illus...

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Detalles Bibliográficos
Autores principales: Zhuo, Youqiong, Yuan, Renyikun, Chen, Xinxin, He, Jia, Chen, Yangling, Zhang, Chenwei, Sun, Kaili, Yang, Shilin, Liu, Zhenjie, Gao, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240219/
https://www.ncbi.nlm.nih.gov/pubmed/34183021
http://dx.doi.org/10.1186/s13020-021-00458-7