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Oxygen concentration affects de novo DNA methylation and transcription in in vitro cultured oocytes
BACKGROUND: Reproductive biology methods rely on in vitro follicle cultures from mature follicles obtained by hormonal stimulation for generating metaphase II oocytes to be fertilised and developed into a healthy embryo. Such techniques are used routinely in both rodent and human species. DNA methyl...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240245/ https://www.ncbi.nlm.nih.gov/pubmed/34183052 http://dx.doi.org/10.1186/s13148-021-01116-3 |