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Oxygen concentration affects de novo DNA methylation and transcription in in vitro cultured oocytes

BACKGROUND: Reproductive biology methods rely on in vitro follicle cultures from mature follicles obtained by hormonal stimulation for generating metaphase II oocytes to be fertilised and developed into a healthy embryo. Such techniques are used routinely in both rodent and human species. DNA methyl...

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Detalles Bibliográficos
Autores principales:	Naillat, Florence, Saadeh, Heba, Nowacka-Woszuk, Joanna, Gahurova, Lenka, Santos, Fatima, Tomizawa, Shin-ichi, Kelsey, Gavin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240245/ https://www.ncbi.nlm.nih.gov/pubmed/34183052 http://dx.doi.org/10.1186/s13148-021-01116-3

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