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Overexpression of lipoic acid synthase gene alleviates diabetic nephropathy of Lepr(db/db) mice
INTRODUCTION: Diabetic nephropathy (DN) develops in about 40% of patients with type 2 diabetes and remains the leading cause of end-stage renal disease. The mechanisms of DN remain to be elucidated. Oxidative stress is thought to be involved in the development of DN but antioxidant therapy has produ...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240563/ https://www.ncbi.nlm.nih.gov/pubmed/34183321 http://dx.doi.org/10.1136/bmjdrc-2021-002260 |