Antiretroviral Tenofovir Induces Senescence-Associated β-Galactosidase Activity in Primary Human Brain Vascular Cells in Multi-Layer Three-Dimensional Co-Culture

Introduction In the current context of early diagnosis of HIV infection, immediate initiation of antiretroviral (ARV) therapy, and lifelong chronic treatment, the potential ARV toxicity is of particular concern. Emtricitabine (FTC) and tenofovir (TFV) are commonly used as backbone drugs in ARV regim...

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Detalles Bibliográficos
Autores principales: Chang, Rachel C, Soontornniyomkij, Benchawanna, Umlauf, Anya, Soontornniyomkij, Virawudh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240677/
https://www.ncbi.nlm.nih.gov/pubmed/34235009
http://dx.doi.org/10.7759/cureus.15327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240677/
https://www.ncbi.nlm.nih.gov/pubmed/34235009
http://dx.doi.org/10.7759/cureus.15327

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