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Antiretroviral Tenofovir Induces Senescence-Associated β-Galactosidase Activity in Primary Human Brain Vascular Cells in Multi-Layer Three-Dimensional Co-Culture
Introduction In the current context of early diagnosis of HIV infection, immediate initiation of antiretroviral (ARV) therapy, and lifelong chronic treatment, the potential ARV toxicity is of particular concern. Emtricitabine (FTC) and tenofovir (TFV) are commonly used as backbone drugs in ARV regim...
Autores principales: | Chang, Rachel C, Soontornniyomkij, Benchawanna, Umlauf, Anya, Soontornniyomkij, Virawudh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240677/ https://www.ncbi.nlm.nih.gov/pubmed/34235009 http://dx.doi.org/10.7759/cureus.15327 |
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