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Nanomechanical sensor for rapid and ultrasensitive detection of tumor markers in serum using nanobody

Early cancer diagnosis requires ultrasensitive detection of tumor markers in blood. To this end, we develop a novel microcantilever immunosensor using nanobodies (Nbs) as receptors. As the smallest antibody (Ab) entity comprising an intact antigen-binding site, Nbs achieve dense receptor layers and...

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Detalles Bibliográficos
Autores principales: Rao, Depeng, Mei, Kainan, Yan, Tianhao, Wang, Yu, Wu, Wenjie, Chen, Ye, Wang, Jianye, Zhang, Qingchuan, Wu, Shangquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tsinghua University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240779/
https://www.ncbi.nlm.nih.gov/pubmed/34221250
http://dx.doi.org/10.1007/s12274-021-3588-4