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Nanomechanical sensor for rapid and ultrasensitive detection of tumor markers in serum using nanobody
Early cancer diagnosis requires ultrasensitive detection of tumor markers in blood. To this end, we develop a novel microcantilever immunosensor using nanobodies (Nbs) as receptors. As the smallest antibody (Ab) entity comprising an intact antigen-binding site, Nbs achieve dense receptor layers and...
Autores principales: | Rao, Depeng, Mei, Kainan, Yan, Tianhao, Wang, Yu, Wu, Wenjie, Chen, Ye, Wang, Jianye, Zhang, Qingchuan, Wu, Shangquan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tsinghua University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240779/ https://www.ncbi.nlm.nih.gov/pubmed/34221250 http://dx.doi.org/10.1007/s12274-021-3588-4 |
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