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WDR62 regulates spindle dynamics as an adaptor protein between TPX2/Aurora A and katanin

WDR62 is a microcephaly-related, microtubule (MT)-associated protein (MAP) that localizes to the spindle pole and regulates spindle organization, but the underlying mechanisms remain elusive. Here, we show that WDR62 regulates spindle dynamics by recruiting katanin to the spindle pole and further re...

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Detalles Bibliográficos
Autores principales: Huang, Junjie, Liang, Zhuobi, Guan, Cuirong, Hua, Shasha, Jiang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240853/
https://www.ncbi.nlm.nih.gov/pubmed/34137789
http://dx.doi.org/10.1083/jcb.202007167