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WDR62 localizes katanin at spindle poles to ensure synchronous chromosome segregation

Mutations in the WDR62 gene cause primary microcephaly, a pathological condition often associated with defective cell division that results in severe brain developmental defects. The precise function and localization of WDR62 within the mitotic spindle is, however, still under debate, as it has been...

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Detalles Bibliográficos
Autores principales: Guerreiro, Amanda, De Sousa, Filipe, Liaudet, Nicolas, Ivanova, Daria, Eskat, Anja, Meraldi, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240857/
https://www.ncbi.nlm.nih.gov/pubmed/34137788
http://dx.doi.org/10.1083/jcb.202007171