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WDR62 localizes katanin at spindle poles to ensure synchronous chromosome segregation
Mutations in the WDR62 gene cause primary microcephaly, a pathological condition often associated with defective cell division that results in severe brain developmental defects. The precise function and localization of WDR62 within the mitotic spindle is, however, still under debate, as it has been...
Autores principales: | Guerreiro, Amanda, De Sousa, Filipe, Liaudet, Nicolas, Ivanova, Daria, Eskat, Anja, Meraldi, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240857/ https://www.ncbi.nlm.nih.gov/pubmed/34137788 http://dx.doi.org/10.1083/jcb.202007171 |
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