Self-assembling HA/PEI/dsRNA-p21 ternary complexes for CD44 mediated small active RNA delivery to colorectal cancer

Our previous work proved that sequence specific double strand RNA (dsRNA-p21) effectively activated p21 gene expression of colorectal cancer (CRC) cells and consequently suppressed CRC growth. However, efficient delivery system is a significant challenge to achieve sufficient therapy. In this study,...

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Detalles Bibliográficos
Autores principales: Feng, Chen-Lin, Han, Yan-Xing, Guo, Hui-Hui, Ma, Xiao-Lei, Wang, Zhi-Qiang, Wang, Lu-Lu, Zheng, Wen-Sheng, Jiang, Jian-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240987/
https://www.ncbi.nlm.nih.gov/pubmed/28994324
http://dx.doi.org/10.1080/10717544.2017.1386732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240987/
https://www.ncbi.nlm.nih.gov/pubmed/28994324
http://dx.doi.org/10.1080/10717544.2017.1386732

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