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Targeted inhibition of human hematological cancers in vivo by doxorubicin encapsulated in smart lipoic acid-crosslinked hyaluronic acid nanoparticles

The chemotherapy of hematological cancers is challenged by its poor selectivity that leads to low therapeutic efficacy and pronounced adverse effects. Here, we report that doxorubicin encapsulated in lipoic acid-crosslinked hyaluronic acid nanoparticles (LACHA-DOX) mediate highly efficacious and tar...

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Detalles Bibliográficos
Autores principales: Zhong, Yinan, Meng, Fenghua, Deng, Chao, Mao, Xinliang, Zhong, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240992/
https://www.ncbi.nlm.nih.gov/pubmed/28958164
http://dx.doi.org/10.1080/10717544.2017.1384864