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Brain targeted oral delivery of doxycycline hydrochloride encapsulated Tween 80 coated chitosan nanoparticles against ketamine induced psychosis: behavioral, biochemical, neurochemical and histological alterations in mice

To develop statistically optimized brain targeted Tween 80 coated chitosan nanoparticulate formulation for oral delivery of doxycycline hydrochloride for the treatment of psychosis and to evaluate its protective effect on ketamine induced behavioral, biochemical, neurochemical and histological alter...

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Detalles Bibliográficos
Autores principales: Yadav, Monu, Parle, Milind, Sharma, Nidhi, Dhingra, Sameer, Raina, Neha, Jindal, Deepak Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241001/
https://www.ncbi.nlm.nih.gov/pubmed/28942680
http://dx.doi.org/10.1080/10717544.2017.1377315