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Reduction-responsive PEtOz-SS-PCL micelle with tailored size to overcome blood–brain barrier and enhance doxorubicin antiglioma effect

A series of novel reduction-responsive micelles with tailored size were designed and prepared to release doxorubicin (DOX) for treating glioma, which were developed based on amphiphilic block copolymer poly (2-ethyl-2-oxazoline)-b-poly (ε-caprolactone) (PEtOz-SS-PCL) and the micelle size could be re...

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Detalles Bibliográficos
Autores principales: Li, Yuling, Baiyang, Li, Leran, Bu, Zhen, Wang, Yandong, Xie, Baixiang, Du, Dandan, Zhu, Yufu, Zhu, Jun, Liang, Rutong, Yu, Hongmei, Liu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241033/
https://www.ncbi.nlm.nih.gov/pubmed/29172749
http://dx.doi.org/10.1080/10717544.2017.1402218