A novel lipid prodrug strategy for sustained delivery of hexadecyloxypropyl 9-[2-(phosphonomethoxy)ethyl]guanine (HDP-PMEG) on unwanted ocular proliferation

Proliferative vitreoretinopathy (PVR) is a blinding eye disease and there is no effective pharmacological measure to prevent PVR development. The difficulty comes from lack of potent antiproliferative agent and lack of sustained delivery to cover high-risk time window for PVR to develop. Lipid prodr...

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Detalles Bibliográficos
Autores principales: Chen, Mei, Hou, Jiangping, Tan, Guilin, Xie, Peng, Freeman, William R., Beadle, James R., Hostetler, Karl Y., Cheng, Lingyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241053/
https://www.ncbi.nlm.nih.gov/pubmed/29115885
http://dx.doi.org/10.1080/10717544.2017.1399303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241053/
https://www.ncbi.nlm.nih.gov/pubmed/29115885
http://dx.doi.org/10.1080/10717544.2017.1399303

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