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Optimization on biodistribution and antitumor activity of tripterine using polymeric nanoparticles through RES saturation

Systemic delivery of tripterine (TPR) is challenged by its insoluble property and unsuitable pharmacokinetics. This work aimed to develop polymeric nanoparticles (NPs) combined with the reticuloendothelial system (RES) saturation to improve the in vivo distribution and antitumor activity of TPR. TPR...

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Detalles Bibliográficos
Autores principales: Yin, Juntao, Wang, Peiqing, Yin, Yuyun, Hou, Yantao, Song, Xiaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241100/
https://www.ncbi.nlm.nih.gov/pubmed/29191042
http://dx.doi.org/10.1080/10717544.2017.1410260