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Optimization on biodistribution and antitumor activity of tripterine using polymeric nanoparticles through RES saturation
Systemic delivery of tripterine (TPR) is challenged by its insoluble property and unsuitable pharmacokinetics. This work aimed to develop polymeric nanoparticles (NPs) combined with the reticuloendothelial system (RES) saturation to improve the in vivo distribution and antitumor activity of TPR. TPR...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241100/ https://www.ncbi.nlm.nih.gov/pubmed/29191042 http://dx.doi.org/10.1080/10717544.2017.1410260 |