Biomimetic synthesis of proline-derivative templated mesoporous silica for increasing the brain distribution of diazepam and improving the pharmacodynamics of nimesulide

Herein a new kind of proline-derivative templated mesoporous silica with curved channels (CMS) was biomimetically synthesized and applied as carrier to improve the drug dissolution and bioavailability of hydrophobic diazepam (DZP) and nimesulide (NMS). Drugs can be incorporated into CMS with high ef...

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Detalles Bibliográficos
Autores principales: Li, Heran, Wang, Jianxin, Cong, Jialiang, Wei, Chen, Li, Jing, Liu, Hongzhuo, Li, Sanming, Yang, Mingshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241142/
https://www.ncbi.nlm.nih.gov/pubmed/28762846
http://dx.doi.org/10.1080/10717544.2017.1359863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241142/
https://www.ncbi.nlm.nih.gov/pubmed/28762846
http://dx.doi.org/10.1080/10717544.2017.1359863

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