Assessment of solid microneedle rollers to enhance transmembrane delivery of doxycycline and inhibition of MMP activity

Many chronic wounds exhibit high matrix metalloproteinase (MMP) activity that impedes the normal wound healing process. Intradermal delivery (IDD) of sub-antimicrobial concentrations of doxycycline, as an MMP inhibitor, could target early stages of chronic wound development and inhibit further wound...

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Detalles Bibliográficos
Autores principales: Omolu, Abbie, Bailly, Maryse, Day, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241162/
https://www.ncbi.nlm.nih.gov/pubmed/28618841
http://dx.doi.org/10.1080/10717544.2017.1337826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241162/
https://www.ncbi.nlm.nih.gov/pubmed/28618841
http://dx.doi.org/10.1080/10717544.2017.1337826

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