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A novel tumor-activated ALA fusion protein for specific inhibition on the growth and invasion of breast cancer cells MDA-MB-231

Objective: The aim of this research was to develop a novel ALA fusion protein for target to the malignant cells surface with high uPAR expression and locally release of the scorpion toxin AGAP in an uPA-cleavable manner. It will provide an effective approach for controlled release of the peptide tox...

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Detalles Bibliográficos
Autores principales: Liu, Xiufeng, Liu, Xintong, Sunchen, Suwen, Liu, Meixia, Shen, Chen, Wu, Juanjuan, Zhao, Wanli, Yu, Boyang, Liu, Jihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241173/
https://www.ncbi.nlm.nih.gov/pubmed/29172777
http://dx.doi.org/10.1080/10717544.2017.1406560