Preliminary study on fabrication, characterization and synergistic anti-lung cancer effects of self-assembled micelles of covalently conjugated celastrol–polyethylene glycol–ginsenoside Rh2

The aim of this study was to develop an amphipathic polyethylene glycol (PEG) derivative that was bi-terminally modified with celastrol and ginsenoside Rh2 (Celastrol-PEG-G Rh2). Such derivative was capable of forming novel, celastrol-loaded polymeric micelles (CG-M) for endo/lysosomal delivery and...

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Detalles Bibliográficos
Autores principales: Li, Peng, Zhou, XiaoYue, Qu, Ding, Guo, Mengfei, Fan, Chenyi, Zhou, Tong, Ling, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241176/
https://www.ncbi.nlm.nih.gov/pubmed/28532223
http://dx.doi.org/10.1080/10717544.2017.1326540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241176/
https://www.ncbi.nlm.nih.gov/pubmed/28532223
http://dx.doi.org/10.1080/10717544.2017.1326540

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