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Passive targeting and lung tolerability of enoxaparin microspheres for a sustained antithrombotic activity in rats

Pulmonary bed can retain microparticles (MP) larger than their capillaries’ diameter, hence we offer a promising way for lung passive targeting following intravenous (IV) administration. In this study, enoxaparin (Enox)-albumin microspheres (Enox-Alb MS) were, optimally, developed as lung targeted s...

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Detalles Bibliográficos
Autores principales: Ibrahim, Shaimaa S., Osman, Rihab, Mortada, Nahed D., Geneidy, Ahmed-Shawky, Awad, Gehanne A. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241188/
https://www.ncbi.nlm.nih.gov/pubmed/28156170
http://dx.doi.org/10.1080/10717544.2016.1245368