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Single synchronous delivery of FK506-loaded polymeric microspheres with pancreatic islets for the successful treatment of streptozocin-induced diabetes in mice

Immune rejection after transplantation is common, which leads to prompt failure of the graft. Therefore, to prolong the survival time of the graft, immunosuppressive therapy is the norm. Here, we report a robust immune protection protocol using FK506-loaded microspheres (FK506(M)) in injectable hydr...

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Detalles Bibliográficos
Autores principales: Pathak, Shiva, Regmi, Shobha, Gupta, Biki, Poudel, Bijay K., Pham, Tung Thanh, Yong, Chul Soon, Kim, Jong Oh, Kim, Jae-Ryong, Park, Min Hui, Bae, Young Kyung, Yook, Simmyung, Ahn, Cheol-Hee, Jeong, Jee-Heon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241191/
https://www.ncbi.nlm.nih.gov/pubmed/28911248
http://dx.doi.org/10.1080/10717544.2017.1377317