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Effective improvement of the neuroprotective activity after spinal cord injury by synergistic effect of glucocorticoid with biodegradable amphipathic nanomicelles

Dexamethasone acetate (DA) produces neuroprotective effects by inhibiting lipid peroxidation and inflammation by reducing cytokine release and expression. However, its clinical application is limited by its hydrophobicity, low biocompatibility and numerous side effects when using large dosage. There...

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Detalles Bibliográficos
Autores principales: Wang, YueLong, Wu, Min, Gu, Lei, Li, XiaoLing, He, Jun, Zhou, LiangXue, Tong, Aiping, Shi, Juan, Zhu, HongYan, Xu, JianGuo, Guo, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241193/
https://www.ncbi.nlm.nih.gov/pubmed/28165815
http://dx.doi.org/10.1080/10717544.2016.1256003