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Effective improvement of the neuroprotective activity after spinal cord injury by synergistic effect of glucocorticoid with biodegradable amphipathic nanomicelles
Dexamethasone acetate (DA) produces neuroprotective effects by inhibiting lipid peroxidation and inflammation by reducing cytokine release and expression. However, its clinical application is limited by its hydrophobicity, low biocompatibility and numerous side effects when using large dosage. There...
Autores principales: | Wang, YueLong, Wu, Min, Gu, Lei, Li, XiaoLing, He, Jun, Zhou, LiangXue, Tong, Aiping, Shi, Juan, Zhu, HongYan, Xu, JianGuo, Guo, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241193/ https://www.ncbi.nlm.nih.gov/pubmed/28165815 http://dx.doi.org/10.1080/10717544.2016.1256003 |
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