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Surfactant protein-A nanobody-conjugated liposomes loaded with methylprednisolone increase lung-targeting specificity and therapeutic effect for acute lung injury

The advent of nanomedicine requires novel delivery vehicles to actively target their site of action. Here, we demonstrate the development of lung-targeting drug-loaded liposomes and their efficacy, specificity and safety. Our study focuses on glucocorticoids methylprednisolone (MPS), a commonly used...

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Detalles Bibliográficos
Autores principales: Li, Nan, Weng, Dong, Wang, Shan-Mei, Zhang, Yuan, Chen, Shan-Shan, Yin, Zhao-Fang, Zhai, Jiali, Scoble, Judy, Williams, Charlotte C., Chen, Tao, Qiu, Hui, Wu, Qin, Zhao, Meng-Meng, Lu, Li-Qin, Mulet, Xavier, Li, Hui-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241200/
https://www.ncbi.nlm.nih.gov/pubmed/29160134
http://dx.doi.org/10.1080/10717544.2017.1402217