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Surfactant protein-A nanobody-conjugated liposomes loaded with methylprednisolone increase lung-targeting specificity and therapeutic effect for acute lung injury
The advent of nanomedicine requires novel delivery vehicles to actively target their site of action. Here, we demonstrate the development of lung-targeting drug-loaded liposomes and their efficacy, specificity and safety. Our study focuses on glucocorticoids methylprednisolone (MPS), a commonly used...
Autores principales: | Li, Nan, Weng, Dong, Wang, Shan-Mei, Zhang, Yuan, Chen, Shan-Shan, Yin, Zhao-Fang, Zhai, Jiali, Scoble, Judy, Williams, Charlotte C., Chen, Tao, Qiu, Hui, Wu, Qin, Zhao, Meng-Meng, Lu, Li-Qin, Mulet, Xavier, Li, Hui-Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241200/ https://www.ncbi.nlm.nih.gov/pubmed/29160134 http://dx.doi.org/10.1080/10717544.2017.1402217 |
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