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Wild Bitter Melon Extract Regulates LPS-Induced Hepatic Stellate Cell Activation, Inflammation, Endoplasmic Reticulum Stress, and Ferroptosis

The activation of hepatic stellate cells (HSCs) is a key component of liver fibrosis. Two antifibrosis pathways have been identified, the reversion to quiescent-type HSCs and the clearance of HSCs through apoptosis. Lipopolysaccharide- (LPS-) induced HSCs activation and proliferation have been assoc...

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Detalles Bibliográficos
Autores principales: Ho, Chang-Hsun, Huang, Jen-Hsuan, Sun, Maw-Sheng, Tzeng, I-Shiang, Hsu, Yi-Chiung, Kuo, Chan-Yen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241502/
https://www.ncbi.nlm.nih.gov/pubmed/34239589
http://dx.doi.org/10.1155/2021/6671129