Cargando…

Wild Bitter Melon Extract Regulates LPS-Induced Hepatic Stellate Cell Activation, Inflammation, Endoplasmic Reticulum Stress, and Ferroptosis

The activation of hepatic stellate cells (HSCs) is a key component of liver fibrosis. Two antifibrosis pathways have been identified, the reversion to quiescent-type HSCs and the clearance of HSCs through apoptosis. Lipopolysaccharide- (LPS-) induced HSCs activation and proliferation have been assoc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ho, Chang-Hsun, Huang, Jen-Hsuan, Sun, Maw-Sheng, Tzeng, I-Shiang, Hsu, Yi-Chiung, Kuo, Chan-Yen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241502/ https://www.ncbi.nlm.nih.gov/pubmed/34239589 http://dx.doi.org/10.1155/2021/6671129

Ejemplares similares

Wild Bitter Melon Extract Abrogates Hypoxia-Induced Cell Death via the Regulation of Ferroptosis, ER Stress, and Apoptosis in Microglial BV2 Cells
por: Lin, Chih-Hung, et al.
Publicado: (2022)

Wild Bitter Melon Leaf Extract Inhibits Porphyromonas gingivalis-Induced Inflammation: Identification of Active Compounds through Bioassay-Guided Isolation
por: Tsai, Tzung-Hsun, et al.
Publicado: (2016)

Wild Bitter Melon Exerts Anti-Inflammatory Effects by Upregulating Injury-Attenuated CISD2 Expression following Spinal Cord Injury
por: Kung, Woon-Man, et al.
Publicado: (2020)

Investigation of Biological Activities of Wild Bitter Melon (Momordica charantia Linn. Var. Abbreviata Ser.)
por: Pham, Thi My Hanh, et al.
Publicado: (2019)

Ferroptosis and endoplasmic reticulum stress in ischemic stroke
por: Li, Yina, et al.
Publicado: (2023)

In Vitro and In Vivo Screening of Wild Bitter Melon Leaf for Anti-Inflammatory Activity against Cutibacterium acnes
por: Chuang, Lu-Te, et al.
Publicado: (2020)

Effect of Superfine Grinding on Antidiabetic Activity of Bitter Melon Powder
por: Zhu, Ying, et al.
Publicado: (2012)

Optimising the Encapsulation of an Aqueous Bitter Melon Extract by Spray-Drying
por: Tan, Sing Pei, et al.
Publicado: (2015)

Effects of Momordica charantia (Bitter Melon) on Ischemic Diabetic Myocardium
por: Czompa, Attila, et al.
Publicado: (2017)

Effectiveness of bitter melon extract in the treatment of ischemic wounds in rats
por: GÜRLEK KISACIK, Öznur, et al.
Publicado: (2018)

The Role of Bitter Melon in Breast and Gynecological Cancer Prevention and Therapy
por: Psilopatis, Iason, et al.
Publicado: (2023)

Bitter melon extract ameliorates palmitate-induced apoptosis via inhibition of endoplasmic reticulum stress in HepG2 cells and high-fat/high-fructose-diet-induced fatty liver
por: Lee, Hwa Joung, et al.
Publicado: (2018)

A case of atrial fibrillation due to Momordica charantia (bitter melon)
por: Erden, Ismail, et al.
Publicado: (2010)

Activation of AMPK by Bitter Melon Triterpenoids Involves CaMKKβ
por: Iseli, Tristan J., et al.
Publicado: (2013)

Metabolomic analysis of the occurrence of bitter fruits on grafted oriental melon plants
por: Zhang, Shuangshuang, et al.
Publicado: (2019)

Diverse roles of bitter melon (Momordica charantia) in prevention of oral cancer
por: Sur, Subhayan, et al.
Publicado: (2021)

Anti-Inflammatory Effect of Charantadiol A, Isolated from Wild Bitter Melon Leaf, on Heat-Inactivated Porphyromonas gingivalis-Stimulated THP-1 Monocytes and a Periodontitis Mouse Model
por: Tsai, Tzung-Hsun, et al.
Publicado: (2021)

The anti-adiposity effect of bitter melon seed oil is solely attributed to its fatty acid components
por: Chen, Gou-Chun, et al.
Publicado: (2017)

Characterization of a Soluble Phosphatidic Acid Phosphatase in Bitter Melon (Momordica charantia)
por: Cao, Heping, et al.
Publicado: (2014)

Beneficial Role of Bitter Melon Supplementation in Obesity and Related Complications in Metabolic Syndrome
por: Alam, Md Ashraful, et al.
Publicado: (2015)

Identification and Characterization of Phenylpropanoid Biosynthetic Genes and Their Accumulation in Bitter Melon (Momordica charantia)
por: Cuong, Do Manh, et al.
Publicado: (2018)

Bitter Melon (Momordica Charantia), a Nutraceutical Approach for Cancer Prevention and Therapy
por: Sur, Subhayan, et al.
Publicado: (2020)

Supercritical fluid extraction of β-carotene from ripe bitter melon pericarp
por: Patel, Avinash Singh, et al.
Publicado: (2019)

Anticancer Activity of Bitter Melon-Derived Vesicles Extract against Breast Cancer
por: Feng, Ting, et al.
Publicado: (2023)

Tetrahydropalmatine attenuates liver fibrosis by suppressing endoplasmic reticulum stress in hepatic stellate cells
por: Xuan, Yuanyuan, et al.
Publicado: (2022)

Autophagy mediated by endoplasmic reticulum stress enhances the caffeine-induced apoptosis of hepatic stellate cells
por: Li, Yongjian, et al.
Publicado: (2017)

Oxymatrine attenuates arsenic-induced endoplasmic reticulum stress and calcium dyshomeostasis in hepatic stellate cells
por: Wang, Huiqun, et al.
Publicado: (2020)

Cryptotanshinone induces apoptosis of activated hepatic stellate cells via modulating endoplasmic reticulum stress
por: Hou, Xiao-Xue, et al.
Publicado: (2023)

An Optimised Aqueous Extract of Phenolic Compounds from Bitter Melon with High Antioxidant Capacity
por: Tan, Sing Pei, et al.
Publicado: (2014)

Bitter melon protects against ER stress in LS174T colonic epithelial cells
por: Kunde, Dale A., et al.
Publicado: (2017)

Bitter Melon (Momordica charantia L.) Supplementation Has No Effect on Hypercholesterolemia and Atherosclerosis in Mice
por: Mohammadmoradi, Shayan, et al.
Publicado: (2020)

A Combination of Melatonin and Ethanol Treatment Improves Postharvest Quality in Bitter Melon Fruit
por: Lin, Xiaoxue, et al.
Publicado: (2020)

Effect of Bitter Melon on Spatial Memory of Rats Receiving a High-Fat Diet
por: Sepehri, Hamid, et al.
Publicado: (2019)

Inhibition of the key metabolic pathways, glycolysis and lipogenesis, of oral cancer by bitter melon extract
por: Sur, Subhayan, et al.
Publicado: (2019)

Phytoradiotherapy to enhance cancer treatment outcomes with cannabidiol, bitter melon juice, and plant hemoglobin
por: Alfonzetti, Tyler, et al.
Publicado: (2023)

Evaluation of acute and sub-chronic toxicity of bitter melon seed extract in Wistar rats
por: Chung, Wan-Yu, et al.
Publicado: (2022)

Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis
por: Dixon, Scott J, et al.
Publicado: (2014)

Malvidin induces hepatic stellate cell apoptosis via the endoplasmic reticulum stress pathway and mitochondrial pathway
por: Ma, Yanhong, et al.
Publicado: (2020)

Antioxidant, cell-protective, and anti-melanogenic activities of leaf extracts from wild bitter melon (Momordica charantia Linn. var. abbreviata Ser.) cultivars
por: Tsai, Tsung-Hsien, et al.
Publicado: (2014)

Momordica charantia (bitter melon) attenuates high-fat diet-associated oxidative stress and neuroinflammation
por: Nerurkar, Pratibha V, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_9tlru8l4mrp26imppivhe5nqvb