3-Alkenyl-2-oxindoles: Synthesis, antiproliferative and antiviral properties against SARS-CoV-2

Sets of 3-alkenyl-2-oxindoles (6,10,13) were synthesized in a facile synthetic pathway through acid dehydration (EtOH/HCl) of the corresponding 3-hydroxy-2-oxoindolines (5,9,12). Single crystal (10a,c) and powder (12a,26f) X-ray studies supported the structures. Compounds 6c and 10b are the most eff...

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Detalles Bibliográficos
Autores principales: Girgis, Adel S., Panda, Siva S., Srour, Aladdin M., Abdelnaser, Anwar, Nasr, Soad, Moatasim, Yassmin, Kutkat, Omnia, El Taweel, Ahmed, Kandeil, Ahmed, Mostafa, Ahmed, Ali, Mohamed A., Fawzy, Nehmedo G., Bekheit, Mohamed S., Shalaby, ElSayed M., Gigli, Lara, Fayad, Walid, Soliman, Ahmed A.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241580/
https://www.ncbi.nlm.nih.gov/pubmed/34243074
http://dx.doi.org/10.1016/j.bioorg.2021.105131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241580/
https://www.ncbi.nlm.nih.gov/pubmed/34243074
http://dx.doi.org/10.1016/j.bioorg.2021.105131

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