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Structure-guided T cell vaccine design for SARS-CoV-2 variants and sarbecoviruses

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants that escape convalescent and vaccine-induced antibody responses has renewed focus on the development of broadly protective T-cell-based vaccines. Here, we apply structure-based network analysis and assessments of...

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Detalles Bibliográficos
Autores principales: Nathan, Anusha, Rossin, Elizabeth J., Kaseke, Clarety, Park, Ryan J., Khatri, Ashok, Koundakjian, Dylan, Urbach, Jonathan M., Singh, Nishant K., Bashirova, Arman, Tano-Menka, Rhoda, Senjobe, Fernando, Waring, Michael T., Piechocka-Trocha, Alicja, Garcia-Beltran, Wilfredo F., Iafrate, A. John, Naranbhai, Vivek, Carrington, Mary, Walker, Bruce D., Gaiha, Gaurav D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241654/
https://www.ncbi.nlm.nih.gov/pubmed/34265281
http://dx.doi.org/10.1016/j.cell.2021.06.029